SERVICES
IDBR OFFERS THE FOLLOWING SERVICES TO COMPANIES AND INSTITUTIONS ON A FEE FOR SERVICE BASIS
Analytical Method development
In-vitro Release Test (IVRT)- Oral and topical dosage forms
Formulation Development
In vitro Permeability Test- Skin, nail and mucous membranes
Stability studies
Physicochemical characterization of APIs and excipients
ANIMAL STUDIES
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Skin sensitivity studies
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Plasma pharmacokinetic studies in animal models
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CNS pharmacokinetics of drugs
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Skin pharmacokinetics of drugs
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Nail pharmacokinetics of drugs
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Pharmacodynamic studies in animal models
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Anti-diabetic activity
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Treatment of Hypetrophic Scars
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Treatment of acute and chronic wounds
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Skin hydration
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Anti inflammatory activity
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Collagen production/denaturation assays
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Antioxidant property
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Bioavailability/Bioequivalence in animal models
CELL CULTURE
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Cell viability assays
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Anticancerous activities
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ELISA
DMPK SERVICES
PHYSICOCHEMICAL PROPERTIES
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Solubility (Thermodynamic and Kinetic method) In buffers of Various pH (PBS, FASSIF, FESSIF, FESGF, FASGF or any assay buffers)
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Simultaneous determination of Log P, Log D and pKa
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Chemical Stability
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Blood Partitioning
ANIMAL PHARMACOKINETICS
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Pharmacokinetics by various routes viz., oral, intravenous, intra-peritoneal, subcutaneous in mice and rats.
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Tissue Distribution
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Mass Balance
IN VITRO PERMEABILITY
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PAMPA
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MDR1-MDCK
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Caco-2
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Skin
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Nail
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Mucous Membrane
PROTEIN BINDING
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Plasma Protein Binding (ultra Filtration and Equilibrium Dialysis)
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Microsomal Protein Binding
IN VITRO METABOLISM
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Metabolic Stability , Liver Microsomes , S-9 Fraction , Cryopreserved Hepatocyte .
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Cytochrome P450 Inhibition
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Plasma Stability
